Alain Fournier

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Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 38-amino acid C-terminally alpha-amidated peptide that was first isolated 20 years ago from an ovine hypothalamic extract on the basis of its ability to stimulate cAMP formation in anterior pituitary cells (Miyata et al., 1989. PACAP belongs to the vasoactive intestinal polypeptide(More)
A recurrent problem in generating realistic pictures by computers is to represent natural irregular objects and phenomena without undue time or space overhead. We develop a new and powerful solution to this computer graphics problem by modeling objects as sample paths of stochastic processes. Of particular interest are those stochastic processes which(More)
We present a simple model for the surface of the ocean, suitable for the modeling and rendering of most common waves where the disturbing force is from the wind and the restoring force from gravity.It is based on the Gerstner, or Rankine, model where particles of water describe circular or elliptical stationary orbits. The model can easily produce realistic(More)
A reflection and refraction model for anisotropic surfaces is introduced. The anisotropy is simulated by small cylinders (added or subtracted) distributed on the anisotropic surface. Different levels of anisotropy are achieved by varying the distance between each cylinder and/or rising the cylinders more or less from the surface. Multidirectional anisotropy(More)
It' has long been known that the complexity of triangulation of simple polygons having an upper bound of 0 (n log n) but a lower bound higher than ~(n) has not been proved yet. We propose here an easily implemented route to the triangulation of simple polygons through the trapezoidization of simple polygons, which is currently done in O(n log n). Then the(More)
Classic radiosity assumes diffuse reflectors in order to consider only pair-wise exchanges of light between elements. It has been previously shown that one can use the same system of equations with separable bi-directional reflection distribution functions (BRDFs), that is BRDFs that can be put in the form of a product of two functions, one of the incident(More)
OBJECTIVE To evaluate perinatal outcome in pregnancies in women with type 1 and type 2 diabetes and the influence of preconception care 10 years after the St. Vincent's declaration. RESEARCH DESIGN AND METHODS A cross-sectional study was conducted in 12 perinatal centers in France in 2000-2001. The main investigated outcomes were perinatal mortality,(More)
The present study was undertaken to investigate the possible antidepressant-like effects of neuropeptide Y (NPY) in the mouse forced swimming test, an animal model widely used for the screening of potential antidepressant drugs. In addition, experiments were performed, using agonists and selective antagonists, to assess the potential role of NPY Y1 and Y2(More)
Selenoproteins contain the essential trace element selenium, the deficiency of which is associated with cancer or accelerated aging. Although selenoproteins are thought to be instrumental for the effects of selenium, the biological function of many of these proteins remains unknown. Here, we studied the role of selenoprotein T (SelT), a selenocysteine (Sec)(More)