Alai Urruticoechea-Uriguen

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The potential to differentiate human embryonic stem cells (hESCs) in vitro to provide an unlimited source of human hepatocytes for use in biomedical research, drug discovery, and the treatment of liver diseases holds great promise. Here we describe a three-stage process for the efficient and reproducible differentiation of hESCs to hepatocytes by priming(More)
Most of applications of embryonic stem (ES) cells require directing differentiation of ES cells to defined cell types. This currently remains a challenge for stem cell biologists though efforts and progresses have been made. The most commonly used method for differentiating ES cells is by initiating the differentiation via embryoid body (EB) formation,(More)
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