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The objective of this study was to determine the T1, T2 and secular-T2 relaxo-volumetric brain aging patterns using multispectral quantitative magnetic resonance imaging, both globally and regionally, and covering an age range approaching the full human lifespan. Fifty-one subjects (28 males, 23 females; age range: 0.5-87 years) were studied consisting of(More)
PURPOSE We examine reporting of nonfatal injury and illness reporting for the two most important sources of such data in the United States: workers' compensation data and the Bureau of Labor Statistics' (BLS) annual Survey of Occupational Injuries and Illnesses. METHODS We linked individual case records from establishments reporting to the BLS with(More)
Although the presence of abnormal late gadolinium enhancement (LGE) in cardiac amyloidosis has been well established, its prognostic implication and utility to identify cardiac involvement in patients with systemic amyloidosis is unknown. The aim of this study was to assess the diagnostic and prognostic significance of cardiovascular magnetic resonance(More)
OBJECTIVE The objective of our study was to compare the diagnostic accuracy of IV contrast-enhanced 64-MDCT with and without the use of oral contrast material in diagnosing appendicitis in patients with abdominal pain. MATERIALS AND METHODS We conducted a randomized trial of a convenience sample of adult patients presenting to an urban academic emergency(More)
PURPOSE To determine the performance of positron emission mammography (PEM), as compared with magnetic resonance (MR) imaging, including the effect on surgical management, in ipsilateral breasts with cancer. MATERIALS AND METHODS Four hundred seventy-two women with newly diagnosed breast cancer who were offered breast-conserving surgery consented from(More)
PURPOSE To retrospectively evaluate the accuracy of multidetector computed tomography (CT) in the diagnosis of perforated acute appendicitis by using surgery and pathologic examination combined as the reference standard. MATERIALS AND METHODS The study was institutional review board approved and HIPAA compliant. Informed patient consent was waived. The(More)
BACKGROUND In patients receiving oral anticoagulation, improved control can reduce adverse outcomes such as stroke and major hemorrhage. However, little is known about patient-level predictors of anticoagulation control. OBJECTIVES To identify patient-level predictors of oral anticoagulation control in the outpatient setting. PATIENTS/METHODS We studied(More)
Abbreviated neuropsychological protocols are increasingly utilized secondary to time-constraints within research and healthcare settings, yet normative data for these abbreviated instruments are lacking. We present geriatric performances and normative data for the Boston Naming Test 30-item even version (BNT-30). Data were utilized from the BU-ADCC registry(More)
OBJECTIVE To characterize symptoms and signs of AL amyloidosis that may bring patients to the attention of rheumatologists, evaluate Ig V(L) gene usage in this subgroup of patients, and assess the impact of soft tissue and bone involvement and V(L) gene usage on survival. METHODS Clinical features of soft tissue and bone involvement were assessed in 191(More)
BACKGROUND The potential to save money within a short time frame provides a more compelling "business case" for quality improvement than merely demonstrating cost-effectiveness. Our objective was to demonstrate the potential for cost savings from improved control in patients anticoagulated for atrial fibrillation. METHODS AND RESULTS Our population(More)