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  • Daisuke Kobayashi, Takashi Nozawa, Kozue Imai, Jun-ichi Nezu, Akira Tsuji, Ikumi Tamai
  • Medicine, Chemistry
  • Journal of Pharmacology and Experimental…
  • 2003 (First Publication: 1 August 2003)
  • Some organic anions are absorbed from the gastrointestinal tract through carrier-mediated transport mechanism(s), which may include proton-coupled transport, anion exchange transport, and others.Expand
  • Takashi Nozawa, Miki Nakajima, +5 authors Tsuyoshi Yokoi
  • Medicine, Chemistry
  • The Journal of pharmacology and experimental…
  • 2002 (First Publication: 1 August 2002)
  • Genetic polymorphisms of human organic anion transporting polypeptides OATP-C (SLC21A6) and OATP-B (SLC21A9) in the Japanese population were analyzed. The allele frequencies of OATP-C*1a, OATP-C*1bExpand
  • Yoshimichi Sai, Yosuke Kaneko, +5 authors Akira Tsuji
  • Medicine, Chemistry
  • Drug Metabolism and Disposition
  • 2006 (First Publication: 1 August 2006)
  • Human organic anion transporting polypeptide OATP-B (OATP2B1) is a pH-sensitive transporter expressed in the apical membranes of small intestinal epithelial cells. In this study, we have examined theExpand
  • Hyakuji Yabuuchi, Ikumi Tamai, +5 authors Akira Tsuji
  • Chemistry, Medicine
  • The Journal of pharmacology and experimental…
  • 1999 (First Publication: 1 May 1999)
  • In the present study, functional characteristics of organic cation transporter (OCTN)1, which was cloned as the pH-dependent tetraethylammonium (TEA) transporter when expressed in mammalian humanExpand
  • Takashi Nozawa, Shigeki Sugiura, +5 authors Ikumi Tamai
  • Medicine, Chemistry
  • Drug metabolism and disposition: the biological…
  • 2004 (First Publication: 1 March 2004)
  • Troglitazone is a thiazolidinedione insulin sensitizer drug that is metabolized mainly to a sulfate conjugate (M-1) in humans. It was reported to cause hepatotoxicity, although the cause has not beenExpand