Akira Shigihara

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Low-concentration halothane or enflurane is generally used for a cesarean section. Sevoflurane is a new volatile anesthetic and its blood/gas partition coefficient is very low. It seems to be suitable for anesthesia that requires rapid induction and emergence, such as cesarean section. In this study sevoflurane was evaluated during anesthesia for cesarean(More)
The shift of oxygen dissociation curve (ODC) and the function of red blood cell after the administration of hypotensive drugs prostaglandin E1 (PGE1), nicardipine (NIC), nitroglycerin, (TNG) were studied in 30 patients in whom mastectomy was performed. The author measured blood gases, blood sugar, L/P, ATP, the deformability of red blood cell, 2,3-DPG, and(More)
Postoperative pain relief and sedation with epidural ketamine were studied. Twenty-four patients for elective upper abdominal surgery were divided into 4 groups. Epidural catheter was inserted into thoracic epidural space before induction of general anesthesia. In each group, either 0.25% bupivacaine 5 ml only, ketamine 0.1 mg.kg-1 + bupivacaine 5 ml, or(More)
The change of analgesic levels, plasma concentrations and the radiographical changes of epidural space due to continuous epidural block were studied in 54 patients receiving pain relief. All the patients received 2 ml per hour of 2% lidocaine or 0.5% bupivacaine via the catheter over two weeks. The effect of epidural block was determined on 1, 2, 4, 7, 10(More)
The effects of mannitol on the function of red blood cell were studied in 12 neurosurgical patients for 4 hours after intravenous administration of 2 g.kg-1 mannitol taking 30 min. After the administration of mannitol, osmotic pressure, Na and K in serum and of red blood cell were all altered. P50, 2, 3-DPG rose gradually and red blood cell deformity(More)
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