Learn More
Glaucoma, a progressive optic neuropathy due to retinal ganglion cell (RGC) degeneration, is one of the leading causes of irreversible blindness. Although glaucoma is often associated with elevated intraocular pressure (IOP), IOP elevation is not detected in a significant subset of glaucomas, such as normal tension glaucoma (NTG). Moreover, in some glaucoma(More)
Glutamate transporters are involved in neural differentiation, neuronal survival, and synaptic transmission. In the present study, we examined glutamate transporter 1 (GLT1) expression in the neonatal somatosensory cortex of C57BL/6 mice, and pursued its role in somatosensory development by comparing barrel development between GLT1 knock-out and control(More)
Glutamate transporters remove glutamate from the extracellular space and maintain it below neurotoxic levels under normal conditions. However, the dynamics under ischemic conditions remain to be determined. In the present study, we evaluated the function of the glial glutamate transporter (GLT-1) during brain ischemia by using an in vivo brain microdialysis(More)
Mirror therapy is one of the promising rehabilitation therapeutic interventions but the neural basis of the therapeutic effect remains unknown. It has been reported that the 20-Hz rhythmic activity is induced in the primary motor cortex after median nerve stimulation and the amount of the induced activity is decreased when the primary motor cortex is(More)
Mirror therapy is an effective technique for pain relief and motor function recovery. It has been demonstrated that magnetic 20-Hz activity is induced in the primary motor cortex (M1) after median nerve stimulation and that the amount of the stimulus-induced 20-Hz activity is decreased when the M1 is activated. In the present study, we investigated how the(More)
Using magnetoencephalography, we measured 20-Hz activity induced after the common peroneal nerve (CPN) stimulation in 15 healthy subjects during the execution of foot movement or its motor imagery, and examined whether the 20-Hz activity is suppressed during motor imagery of foot movement. The prominent 20-Hz activity was contralaterally induced in the(More)
The neural mechanisms underlying recognition of presented hand actions are not well understood. Rolandic rhythmic activity of about 20 Hz is reproducibly induced after median nerve stimulation and has been reported to be related to various types of movements including actual movement, motor imagery and action observation. We recorded neuromagnetic brain(More)
Research on patient-reported outcomes indicates that constipation is a common adverse effect of chemotherapy, and the use of 5-hydroxytryptamine (serotonin; 5HT3) receptor antagonists aggravates this condition. As cancer patients take multiple drugs as a part of their clinical management, a non-pharmacological self-management (SM) of constipation would be(More)
  • 1