Akira KOBATA

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Comparative study of the oligosaccharide profiles of individual human milk revealed the presence of three different patterns. Four oligosaccharides containing the Fucalpha1-2Gal group were missing in the milk of non-secretor, and three oligosaccharides containing the Fucalpha1-4GlcNAc group were missing in the milk of Lewis negative individuals.(More)
Dystoroglycan is encoded by a single gene and cleaved into two proteins, alpha and beta-dystroglycan, by posttranslational processing. The 120kDa peripheral nerve isoform of alpha-dystroglycan binds laminin-2 comprised of the alpha 2, beta 1, and gamma 1 chains. In congenital muscular dystrophy and dy mice deficient in laminin alpha 2 chain, peripheral(More)
Glycoproteins, which react with Lens culinaris agglutinin, in the membrane preparation of various portions of brains and spinal cords, obtained from 9-week-old rats and 29-month-old rats, were comparatively analyzed by SDS-polyacrylamide gel electrophoresis. In contrast to the samples from brain, which showed similar staining patterns in the two different(More)
The sugar chains of bovine rhodopsin released from opsin by hydrazinolysis were reduced with NaB((3)H)(4) and fractionated by paper chromatography. Three oligosaccharides were obtained. The structure of the major ((3)H)-oligosaccharide (ca. 60% of total) was elucidated by sequential exoglycosidase digestion, methylation analysis and endo-?-N-acetyl(More)
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