Akio Kikuta

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Formaldehyde is a flammable, colorless and readily polymerized gas at ambient temperature, and is one of the major pollutants in indoor air. Medical students during their dissection course are exposed to formaldehyde, whose exposure is recently considered to be one of the causes of multiple chemical sensitivity. To understand the system that produces(More)
Left ventricular (LV) myocardial slices were isolated from murine hearts (300 microm thick) and were stimulated at 1 Hz without external load. Mean myocardial slice O(2) consumption (MVo(2)) per minute (mMVo(2)) without stimulation was 0.97 +/- 0.14 ml O(2).min(-1).100 g LV(-1) and mean mMVo(2) with stimulation increased to 1.80 +/- 0.17 ml O(2).min(-1).100(More)
Cardiac sarcoplasmic reticulum (SR) Ca2+-ATPase (SERCA2a) is responsible for most of the Ca2+ removal during diastole and a larger Ca2+ handling energy consumer in excitation–contraction (E–C) coupling. To understand the cardiac performance under long-term SERCA2a overexpression conditions, we established SERCA2a transgenic (TG) Wistar rats to analyze(More)
The aim of the present study was to examine the effects of formaldehyde solution on rat left ventricular function and compare it with those in hypertrophic hearts treated with isoproterenol by pressure-volume measurements with the catheter method. After 20-30 min. of intravenous infusion of 3.7% formaldehyde solution (FA) at 10 μl (3.7 mg)/kg/min, normal(More)
Reducing the levels of formaldehyde (FA) exposure in gross anatomy laboratories has been urgently required. We improved the environment of our gross anatomy laboratory by changing the existing general ventilation to local ventilation. We developed a local ventilation apparatus (grid-type of hood with downward suction) that can be attached to an ordinary(More)