Akiko Sanada

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PURPOSE The present study aimed to clarify the relationship between deficits in knee-flexion torque and morphological changes in the semitendinosus muscle-tendon complex after harvesting the semitendinosus tendon for anterior cruciate ligament (ACL) reconstruction. METHODS Isometric knee-flexion torque at 45 and 90 degrees of knee flexion was measured in(More)
A 61-year-old woman had recurrent syncopal attacks caused by torsades de pointes associated with remarkable QT prolongation (QTc = 740 ms). Left ventriculography showed apical akinesis (ballooning) and basal hyperkinesis, but coronary angiography was normal. This was compatible with takotsubo cardiomyopathy. The wall motion of the left ventricle (LV)(More)
OBJECTIVE To assess the incidence, characteristics, and prognosis of ventricular tachyarrhythmia in hypertrophic cardiomyopathy (HCM). PATIENTS The study consisted of 66 consecutive patients with HCM who were admitted to Niigata University Hospital between 1992 and 2005. Their clinical characteristics and ECG morphology were investigated according to the(More)
A 39-year-old man received implantable cardioverter defibrillator (ICD) shocks during sinus rhythm, triggered by an increase in amplitude and oversensing of intracardiac T waves, caused by hyperkalemia. After treatment of hyperkalemia, the T wave morphology normalized, and oversensing and inappropriate ICD shocks were eliminated. Alteration of the(More)
To evaluate whether it is useful for diagnosis to detect K-ras and p53 mutations in biopsy specimens and bile of biliary tract lesions, 12 cholangiocarcinomas (CC), eight cases of cholangitis, seven gallbladder carcinomas (GBC), seven gallbladder cholesterol polyps, four cases of adenomyomatosis of the gallbladder and five cases of cholecystitis were(More)
BACKGROUND Bepridil (a multiple channel blocker) may markedly prolong the QT interval and induce polymorphic ventricular tachyarrhythmias (VTA). We compared the transmural ventricular repolarization characteristics and inducibility of polymorphic VTA after administration of bepridil versus the pure I(Kr) blocker, E-4031, each administered to five open-chest(More)
BACKGROUND Because bepridil blocks multiple myocardial ionic channels, including the muscarinic acetylcholine receptor-operated potassium current (I(KAch)), bepridil is expected to suppress atrial fibrillation (AF) mediated by vagal nerve stimulation (VNS). METHODS AND RESULTS The therapeutic effects of bepridil were studied with a special focus on heart(More)
In contrast to the atrial septal defect (ASD) as a congenital interatrial shunt, the extracardiac interatrial tunnel is extremely rare. We report the first percutaneous closure of this entity during closure of a secundum ASD after careful investigation of ischemic risk in a 15-year-old girl. The extracardiac interatrial tunnel could entail interatrial(More)
A 62-year-old man was admitted because of repetitive episodes of syncope attacks. In 2003, he had undergone surgical removal of esophageal cancer followed by poststernum reconstruction of the stomach. Repetitive electrocardiogram (ECG) recordings demonstrated that the coved-type ST segment elevation was induced after but not before meals (Fig. 1A and B).(More)