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  • Frederic A. Fellouse, Kaori Esaki, +9 authors Sachdev S. Sidhu
  • Biology, Medicine
  • Journal of molecular biology
  • 2007 (First Publication: 1 November 2007)
  • We have previously established a minimalist approach to antibody engineering by using a phage-displayed framework to support complementarity determining region (CDR) diversity restricted to a binaryContinue Reading
  • Jun Huang, Koki Makabe, Matthew Biancalana, Akiko Koide, Shohei Koide
  • Biology, Medicine
  • Journal of molecular biology
  • 2009 (First Publication: 1 October 2009)
  • We have established a new protein-engineering strategy termed "directed domain-interface evolution" that generates a binding site by linking two protein domains and then optimizing the interfaceContinue Reading