• Publications
  • Influence

Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage your publications. Semantic Scholar automatically creates author pages based on data aggregated from public sources and our publisher partners.
  • Shu-Ming Huang, Akihiro Mouri, +9 authors Nobuhisa Iwata
  • Biology, Medicine
  • Journal of Biological Chemistry
  • 2006 (First Publication: 24 April 2006)
  • A subtle but chronic alteration in metabolic balance between amyloid-β peptide (Aβ) anabolic and catabolic activities is thought to cause Aβ accumulation, leading to a decade-long pathologicalContinue Reading
  • Akihiro Mouri, Yukihiro Noda, Takeshi Enomoto, Toshitaka Nabeshima
  • Medicine, Biology
  • Neurochemistry International
  • 2007 (First Publication: 1 July 2007)
  • In humans, phencyclidine (PCP), a non-competitive N-methyl-d-aspartate (NMDA) receptor antagonist, reproduces a schizophrenia-like psychosis including positive symptoms, negative symptoms andContinue Reading
  • Yoshimasa Yamaguchi, Hitoshi Miyashita, +6 authors Toshitaka Nabeshima
  • Chemistry, Medicine
  • Journal of Pharmacology and Experimental…
  • 2006 (First Publication: 1 June 2006)
  • We have previously shown that intracerebroventricular (i.c.v.) infusion of amyloid-β (Aβ)1–40 produces oxidative stress and cholinergic dysfunction, as well as learning and memory deficits, in rats.Continue Reading
  • Akihiro Mouri, Yukihiro Noda, Hideo Hara, Hiroyuki Mizoguchi, Takeshi Tabira, Toshitaka Nabeshima
  • Medicine
  • FASEB journal : official publication of the…
  • 2007 (First Publication: 1 July 2007)
  • Immunotherapy with Abeta is expected to bring great improvement for Alzheimer disease (AD). However, clinical trials have been suspended because of meningoencephalitics, which accompanied lymphocyticContinue Reading
  • M Ikeda, Yasuyuki Tomita, Akihiro Mouri, Minori Koga, Nakao Iwata
  • Medicine, Biology
  • Biological Psychiatry
  • 2010 (First Publication: 1 February 2010)
  • BACKGROUND Pharmacogenomic approaches based on genomewide sets of single nucleotide polymorphisms (SNPs) are now feasible and offer the potential to uncover variants that influence drug response. Continue Reading
  • Ping Jung Lu, Takayoshi Mamiya, +7 authors Toshitaka Nabeshima
  • Medicine, Chemistry
  • Journal of Pharmacology and Experimental…
  • 2009 (First Publication: 1 October 2009)
  • In Alzheimer’s disease (AD), the deposition of amyloid peptides is invariably associated with oxidative stress and inflammatory responses. Silibinin (silybin), a flavonoid derived from the herb milkContinue Reading
  • Hiroyuki Mizoguchi, Kazuhiro Takuma, +9 authors Kiyofumi Yamada
  • Chemistry, Medicine
  • Journal of Pharmacology and Experimental…
  • 2009 (First Publication: 1 October 2009)
  • In Alzheimer's disease (AD), the expression of matrix metalloproteases (MMPs), which are capable of degrading extracellular matrix proteins, is increased in the brain. Previous studies with culturedContinue Reading