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A detailed analysis of 219 total knee arthroplasties performed with a single implant design was performed. Factors significantly affecting the postoperative range of motion of total knee arthroplasties 2 years after surgery included preoperative diagnosis and preoperative range of motion. Sex, age, body mass index, femoral component size, posterior cruciate(More)
Osteoarthritis is the most common form of human arthritis. We investigated the potential role of asporin, an extracellular matrix component expressed abundantly in the articular cartilage of individuals with osteoarthritis, in the pathogenesis of osteoarthritis. Here we report a significant association between a polymorphism in the aspartic acid (D) repeat(More)
alpha-Tricalcium phosphate (alpha-TCP)/dicalcium phosphate dibasic (DCPD)/tetracalcium phosphate monoxide (TeCP) cement was implanted in paste form into soft tissue (rate subcutaneous sockets) and bone tissue (defects in rabbit mandibles) to evaluate the setting behaviour of the cement and tissue responses to the cement. A histological study of the soft(More)
OBJECTIVE We report alteration of the temporomandibular joint disk and the condyle position through the construction of a mandibular full-coverage occlusal appliance (often referred to as a disk repositioning appliance). STUDY DESIGN Forty-five joints with displaced disks with reduction were available for the study. We assessed these joints for disk(More)
OBJECTIVE The purpose of this study was to evaluate disk repositioning clinically and through use of magnetic resonance imaging after the insertion of a disk repositioning appliance. STUDY DESIGN Seventy-four patients with 82 temporomandibular joints showing middle to late opening movement click and closing movement click near maximum intercuspation were(More)
Prehardened calcium phosphate cement consisting of alpha-tricalcium phosphate (alpha-TCP), dicalcium phosphate dibasic (DCPD) and tetracalcium phosphate monoxide (TeCP) was implanted in rabbit mandibles and back muscles, and studied histologically and microradiographically. In the mandibles, new bone formation occurred around the implants and increased in(More)
PURPOSE The purpose of this retrospective study was to evaluate the effect of maxillary full-coverage occlusal splint (stabilization splint) therapy for specific temporomandibular disorders and their symptoms/signs. MATERIAL AND METHODS This study assessed the outcome of 232 patients who were suffering from chronic pain on movements, joint noise except(More)
Susceptibility to osteoarthritis, the most common human arthritis, is known to be influenced by genetic factors. Through a genome-wide association study using approximately 100,000 SNPs, we have identified a previously unknown gene on chromosome 3p24.3, DVWA, which is associated with susceptibility to knee osteoarthritis. Expressed specifically in(More)
Osteoarthritis (OA), a common skeletal disease, is a leading cause of disability among the elderly populations. OA is characterized by gradual loss of articular cartilage, but the etiology and pathogenesis of OA are largely unknown. Epidemiological and genetic studies have demonstrated that genetic factors play an important role in OA. To identify(More)
Calcium phosphate cement consisting of alpha-tricalcium phosphate (alpha-TCP), dicalcium phosphate dibasic (DCPD) and tetracalcium phosphate monoxide (TeCP) was implanted into surgically created full-thickness defects in the cranial bone (bone defect experiment) and directly onto the cranial bone under the periosteum (augmentation experiment). Three months(More)