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After axotomy, application of muscimol, a GABA(A) receptor agonist, induced an increase in intracellular Ca(2+) ([Ca(2+)](i)) in dorsal motor neurons of the vagus (DMV neurons). Elevation of [Ca(2+)](i) by muscimol was blocked by bicuculline, tetrodotoxin, and Ni(2+). In axotomized DMV neurons measured with gramicidin perforated-patch recordings, reversal(More)
Dentine permeability determinations were made longitudinally in cavities prepared in dog teeth in vivo, using two different techniques: isotope clearance and fluid filtration. Measurements made with both techniques indicate that there is a large reduction in dentine-permeability within the first week following cavity preparation. The phenomenon requires an(More)
Cavities were cut in both lower molars of 11 anaesthetized dogs. Dentine permeability was quantitated in these teeth using a filtration technique before and after acid etching to remove the smear layer. Acid-etching increased 5-fold the ease with which fluid could flow across dentine. Under conditions of high fluid filtration, an opening into the pulp(More)
To investigate the long-term biological effect of extreme low dose ionising radiation, we irradiated normal human fibroblasts (HFLIII) with carbon ions (290 MeV u(-1), 70 keV microm(-1)) and gamma-rays at 1 mGy (total dose) once at a low dose rate (1 mGy 6-8 h(-1)), and observed the cell growth kinetics up to 5 months by continuous culturing. The growth of(More)
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