Akihide Kurita

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Our previous study demonstrated that dexmedetomidine drastically reduced mortality and inhibited the inflammatory response during endotoxemia in rats. The aim of this study was to clarify the dose- and time-related effects of dexmedetomidine on mortality and inflammatory responses to endotoxemia in rats. Male Wistar rats (n = 96) were anesthetized(More)
To clarify the dose-related effects of direct hemoperfusion using a cytokine adsorbent column (CTR) on the mortality and inflammatory responses to endotoxin-induced shock in rats. Prospective and randomized study. University research laboratory. Male Wistar rats. Forty-eight rats were injected intravenously with Escherichia coli endotoxin (15 mg/kg over 2(More)
The present study compared the effects of direct hemoperfusion (DHP) using a cytokine absorbing (CTR) column with those using an endotoxin absorbing (PMX) column with endotoxin-induced shock in rats. Thirty-six rats were injected intravenously with endotoxin (15 mg/kg), and then allocated into one of the following three groups: control group, treated(More)
OBJECTIVE The purpose of the present study was to investigate osseointegration using radiographs of titanium (Ti) implants into the osteoporotic mandible of rats. MATERIALS AND METHODS Rats were divided into three groups: first group, which were fed a standard diet throughout (control group), second group which were fed a Ca-deficient diet for only 1 week(More)
A patient developed persistent disturbance of consciousness after uneventful clipping of an unruptured cerebral aneurysm under general anesthesia. Pseudohypoxic brain swelling (PHBS) was suspected because computerized tomography (CT) and magnetic resonance imaging (MRI) revealed diffuse brain swelling, especially in the bilateral basal ganglia and thalami.(More)
A 74-year-old man was scheduled for laparoscopic low anterior resection of rectal cancer. Preoperative blood coagulation test showed his prothrombin time (PT) and activated partial thromboplastin time (APTT) remarkably prolonged. However, he experienced only slight epistaxis. Further examination suggested the presence of acquired factor V inhibitor.(More)
A 3-month-old infant was scheduled for video-assisted thoracoscopic surgery for sequestration of the right lung. One-lung ventilation was performed with our handmade double-lumen tube. Intubation was performed easily using a laryngeal fiberscope and X-ray fluoroscopy. Good thoracoscopic view was obtained with simple deflation of the right lung.(More)
BACKGROUND Carvedilol is a nonselective β-adrenoceptor and selective α(1)-adrenoceptor blocker and is widely used in the treatment of patients with hypertensive and/or chronic heart failure because, unlike classic β-blockers, this drug has additional endothelium-dependent vasodilatory effects. We evaluated the effects of oral administration of carvedilol on(More)