A pH sensitive artificial ion channel, tetracyanoresorcinarene, whose pK(a1) to pK(a3) are around pH 7, was synthesized. Conductivities for potassium ion were increased by the progress of dissociation at the channel mouth.
Voltage-dependent artificial ion channels 3 and 4 were synthesized. Two cholic acid derivatives were connected through a m-xylylene dicarbamate unit at 3-hydroxyl groups. Asymmetries were introduced by terminal hydrophilic groups, carboxylic acid and phosphoric acid for 3 and hydroxyl and carboxylic acid for 4. Under basic conditions, these headgroups in 3… (More)