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BACKGROUND Optic perineuritis is an uncommon variety of orbital inflammatory disease that is distinct from demyelinating optic neuritis. OBJECTIVE To describe the clinical and radiographic features of idiopathic optic perineuritis, with particular emphasis on those features that help to distinguish this condition from optic neuritis. METHODS We reviewed(More)
PURPOSE Afferent asymmetry of visual function is detectable in both normal and pathologic conditions. With a computerized test, we assessed the variability in measuring afferent asymmetry of the pupillary light reflex, that is, the relative afferent pupillary defect. METHODS In ten normal subjects, pupillary responses to an alternating light stimulus were(More)
PURPOSE To determine whether the relative afferent pupillary defect (RAPD) remains constant over time in normal subjects. METHODS Seventeen normal subjects were tested with infrared pupillography and automated perimetry in four sessions over 3 years. The changes in RAPD and visual field asymmetry between testing sessions were compared. RESULTS The range(More)
BACKGROUND In patients with outer retinal degeneration, a differential pupil response to long wavelength (red) versus short wavelength (blue) light stimulation has been previously observed. The goal of this study was to quantify differences in the pupillary re-dilation following exposure to red versus blue light in patients with outer retinal disease and(More)
OBJECTIVES To characterize the pathogenesis and clinical features of optic disc edema associated with obstructive sleep apnea syndrome (SAS). METHODS A series of 4 patients with SAS and papilledema (PE) underwent complete neuro-ophthalmologic evaluation and lumbar puncture. In 1 patient, continuous 24-hour intracranial pressure (ICP) monitoring was also(More)
OBJECTIVE To identify a distinctive chronic visual complication of lysergic acid diethylamide (LSD) use. DESIGN Description of the clinical findings in three patients with this disorder. SETTING A neuro-ophthalmology referral center. RESULTS All three patients experienced prolonged afterimages (palinopsia) during LSD intoxication and have continued to(More)
OBJECTIVE To weight the rod-, cone-, and melanopsin-mediated activation of the retinal ganglion cells, which drive the pupil light reflex by varying the light stimulus wavelength, intensity, and duration. DESIGN Experimental study. PARTICIPANTS Forty-three subjects with normal eyes and 3 patients with neuroretinal visual loss. METHODS A novel stimulus(More)
To clarify the appropriate role of lumboperitoneal (LP) shunting in the surgical management of pseudotumor cerebri (PTC), we retrospectively analyzed the clinical data from 30 patients who underwent this procedure. We found LP shunting to be an effective means of acutely lowering intracranial pressure. Symptoms of increased intracranial pressure improved in(More)
BACKGROUND This study was undertaken to determine the natural history of untreated skull base meningiomas. Although there are reports on the natural history of meningiomas, most series contain only a few cases of meningiomas involving the skull base. Natural history information is important when recommending treatment and evaluating results. METHODS The(More)
BACKGROUND There have been anecdotal reports of anterior ischemic optic neuropathy (AION) occurring in eyes with optic disc drusen (ODD), but the clinical features of this condition have not been well characterized. OBJECTIVES To better describe the clinical features of AION associated with ODD and to compare the clinical features of this condition with(More)