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We identified the sequence-specific starting positions of consecutive miscalls in the mapping of reads obtained from the Illumina Genome Analyser (GA). Detailed analysis of the miscall pattern indicated that the underlying mechanism involves sequence-specific interference of the base elongation process during sequencing. The two major sequence patterns that(More)
Protein-protein interactions play key roles in protein function and the structural organization of a cell. A thorough description of these interactions should facilitate elucidation of cellular activities, targeted-drug design, and whole cell engineering. A large-scale comprehensive pull-down assay was performed using a His-tagged Escherichia coli ORF clone(More)
metabolites of the plant kingdom have long been important as leading precursors in the pharmaceutical industry (Simmond and Grayer 1999). Reconstruction of biopathways in plants plays key roles in effectively biosynthesizing those precursors, but rational engineering of secondary metabolic pathways in plants requires a thorough knowledge of the whole(More)
Jamu is Indonesian herbal medicine made from a mixture of several plants. Some plants perform as main ingredients and the others as supporting ingredients. By utilizing biplot configuration, we explored the relationship between Indonesian herbal plants and the efficacy of jamu. Among 465 plants used in 3138 jamu, we determined that 190 plants were(More)
—Motivation: Wiki-based databases are becoming popular in biology research, but many of them do not provide a measure to control vocabulary (ontology) of input data despite their use in multiuser environment. We present an extension to MediaWiki, the most popular wiki-based platform, which realizes implementation of word checks and data integration at the(More)
BACKGROUND Orbital adenocarcinoma is a relatively rare, primary orbital malignant epithelial tumor, and shares the poor prognosis of orbital adenoid cystic carcinoma. We report the cases of two patients with orbital adenocarcinoma who were treated with heavy charged carbon particle irradiation and followed up for more 6 years. METHOD Two patients with(More)
A wiki-based repository for crude drugs and Kampo medicine is introduced. It provides taxonomic and chemical information for 158 crude drugs and 348 prescriptions of the traditional Kampo medicine in Japan, which is a variation of ancient Chinese medicine. The system is built on MediaWiki with extensions for inline page search and for sending user-input(More)
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