Akanksha Yadav

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Rituximab (MabThera™, Roche) is a chimeric IgG1 monoclonal antibody targeting the CD20 surface antigen on normal and neoplastic B cells. It revolutionized the treatment of non-Hodgkin’s lymphoma with superior progression-free and overall survival. However, its prohibitively high cost makes it inaccessible to majority of patients in developing countries.(More)
To compare the pharmacokinetics of 13-cis retinoic acid (13-cisRA) between Indian and UK neuroblastoma patients receiving comparable treatment, alongside measures of toxicity and response. 13-cisRA (160 mg/m2/day) was administered to 36 patients ≤16 years in two divided doses. Plasma 13-cisRA concentrations were determined on days 1 and 14 of cycles 1 and 4(More)
INTRODUCTION The role of trace elements in various diseases has been a matter of controversy with various authors reporting on conflicting data. They are receiving much attention in the detection of oral cancer and precancer as they are found to be significantly altered and have an important role in carcinogenesis. Trace elements have been extensively(More)
Endodontically treated molars with almost total coronal destruction may be salvageable by using multiple posts in divergent canals. The fabrication of dowel and core for multirooted teeth can be a vexing problem, especially when there is minimal coronal dentin. A number of methods have been suggested for making a cast dowel and core using two or more of the(More)
This report describes the case of a 42 years old male patient whose one right hand finger was partially lost as a result of occupational trauma. A modified impression technique was used for impression making and wax pattern was fabricated using the normal hand of the same patient. A special type of wax was formulated to make a pattern which was easily(More)
This article describes a clinical case report of a 65-year-old male patient in which an overdenture was fabricated by using a simple, logical and inexpensive means of retentive device. The described mandibular overdenture involves a simple modification in the coping design and a wire lock mechanism which was fabricated during denture processing. The(More)
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