Akaash Kumar Mishra

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Plants like Arabidopsis thaliana are convenient model systems to study fundamental questions related to regulation of the stress transcriptome in response to stress challenges. Microarray results of the Arabidopsis transcriptome indicate that several genes could be upregulated during multiple stresses. High-salinity, drought, and low temperature are three(More)
Platinum-based chemotherapeutics exert their therapeutic efficacy via the formation of DNA adducts which interfere with DNA replication, transcription and cell division and ultimately induce cell death. Repair and tolerance of these Pt-DNA lesions by nucleotide excision repair (NER) and homologous recombination (HR) can substantially reduce the(More)
UNLABELLED In the recent past, there has been a resurgence of interest in Chikungunya virus (CHIKV) attributed to massive outbreaks of Chikungunya fever in the South-East Asia Region. This has reflected in substantial increase in submission of CHIKV genome sequences to NCBI (National Center for Biotechnology Information) database. Hereby we submit a(More)
encouragement and personal guidance have provided a good basis for the present thesis. I am thankful to my committee members – Dr. Catherine Sears for bestowing their loving attitude towards me and guiding me whenever required. A special appreciation for Robin Dewalt and Dr. Cecilia Devlin who helped me by generously sharing the lab supplies and guiding me(More)
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