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—In this paper, we report on the design, fabrication, and characterization of an in-plane mode-matched tuning-fork gyroscope (M 2-TFG). The M 2-TFG uses two high-quality-factor (Q) resonant flexural modes of a single crystalline silicon mi-crostructure to detect angular rate about the normal axis. Operating the device under mode-matched condition, i.e.,(More)
Chromatin acts as a natural barrier in DNA-damage recognition and repair. Histones undergo differential post-translational modification(s) to facilitate DNA damage response (DDR). Importance of modifications like phosphorylation of histone variant H2A.X in DNA repair is very well understood, however, ambiguous results exist in literature regarding the(More)
The effect of solvent conditions on the aggregation of IgM in serum specimens from patients with macroglobulinemia was studied by a turbidimetric procedure. Aggregation of IgM varied considerably among the samples and was affected by a number of experimental parameters. In general, IgM aggregation was more pronounced under acidic conditions and in solvents(More)
—In this paper, the design, implementation and characterization of a continuous time transimpedance-based ASIC for the actuation and sensing of a high-MEMS tuning fork gyroscope (TFG) is presented. A T-network transimpedance amplifier (TIA) is used as the front-end for low-noise, sub-atto-Farad capacitive detection. The T-network TIA provides on-chip(More)
A simple spectrophotometric method for the sequential determination of triglycerides and cholesterol from a single serum sample was developed. In this two-stage procedure, the triglycerides and cholesterol esters are first hydrolysed to glycerol and free cholesterol respectively, with simultaneous scavenging of the liberated free fatty acids, a technique(More)
A small drug molecule, L-DOPA, was converted into well-defined dendritic macromolecules. Their monodisperse nature was shown by NMR, MALDI-TOF-MS, and PAGE. A third-generation L-Dopa dendrimer contained 30 L-Dopa residues, which made up its core, branches, and periphery. Individual L-Dopa moieties in the dendrimer were connected to one another via(More)
This paper presents the design and implementation of an in-plane solid-mass single-crystal silicon tuning fork gyro that has the potential of attaining sub-deg/hr rate resolutions. A design is devised to achieve high Q in the drive and sense resonant modes (Q drive =81,000 and Q sense =64,000) with effective mode decoupling. The gyroscope was fabricated on(More)
A CMOS ASIC has been designed and interfaced with a high Q MEMS gyroscope to yield an angular rate sensor with a 1.2deg/hr noise floor and 2mV/deg/s rate sensitivity. A T-network transimpedance amplifier (TIA) has been implemented with a measured capacitive resolution of 0.04aF/radicHz, an SNDR of 104dB and which consumes ~ 400muW of power. The TIA also(More)
Micromachined gyroscopes constitute one of the fastest growing segments of the microsensor market. The application domain of these devices is quickly expanding from automotive to consumer and personal navigation systems. Examples include anti-skid and safety systems in cars, and image stabilization in digital cameras. Today, MEMS gyros do not meet the(More)
The capacity for specific binding of 125I-epidermal growth factor (EGF) was studied in crude membrane fractions from 95 human breast carcinomas. About 42% of the samples showed saturable, high affinity, specific binding of EGF. In 21% of the tumors we were able to demonstrate high (above 10 fmoles/mg protein) binding capacity. Moreover, high EGF receptor(More)