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The process of epithelial-mesenchymal transition (EMT), in addition to being an initiating event for tumor metastasis, is implicated in conferring several clinically relevant properties to disseminating cancer cells. These include stem cell-like properties, resistance to targeted therapies and ability to evade immune surveillance. Enrichment analysis of(More)
Circulating tumor cells (CTCs) have shown prognostic relevance in many cancer types. However, the majority of current CTC capture methods rely on positive selection techniques that require a priori knowledge about the surface protein expression of disseminated CTCs, which are known to be a dynamic population. We developed a microfluidic CTC capture chip(More)
and using the sensor indicator value to communicate inaccuracies within navigation software was investigated. Novel hybrid tracker configurations included use of the Window FG with infrared and/or video-based trackers. Results The fiducial registration error (FRE) between fiducials on the vertical phantom and divot targets was mm for the conventional(More)
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