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Benzodiazepines are the most commonly prescribed psychotropic drug in the elderly. Benzodiazepines with a long duration of action can produce marked sedation and psychomotor impairment in older people, and are associated with an increased risk of hip fracture and of motor vehicle crash. One thousand seven hundred and one individuals of 65 years and over,(More)
OBJECTIVE Both loneliness and social networks have been linked with mood and wellbeing. However, few studies have examined these factors simultaneously in community-dwelling participants. The aim of this study was to examine the relationship between social network, loneliness, depression, anxiety and quality of life in community dwelling older people living(More)
OBJECTIVES The aim of this study was to examine the sensitivities and specificities of the clock drawing test (CDT) in the detection of dementia among older people in primary care, with particular emphasis on the effect of depression on CDT specificity. Most previous studies have been sited in specialist settings and few have addressed the issue of(More)
BACKGROUND Depression is the most common mental disorder in the community-dwelling elderly. AIMS To determine the three-year prognosis of depression in a cohort of 127 community-dwelling elderly subjects and identify factors relevant to outcome. METHOD The subjects, diagnosed depressed at year 0 using the GMS-AGECAT package, were followed up three years(More)
BACKGROUND The relationship between suicide rates and the religious climate of a community is a matter of controversy. Rising suicide rates have been attributed in part to a decline in religious observance, but contradictory evidence has also been adduced. METHODS We compared national suicide rates, classified according to gender, age, and urban-rural(More)
OBJECTIVE Measurement of medial temporal lobe atrophy (MTL) by computerised tomography (CT) may be a useful adjunct to the diagnosis of AD. The aim of this study was to assess the sensitivity, specificity, predictive values and diagnostic accuracy of CT measurement of MTL thickness for patients with probable AD, compared with a 'diseased' control group, and(More)
BACKGROUND It has been reported that late onset depression is more frequently associated with acquired organic pathology and that patients are less likely to report a family history of depression. Differences in phenomenology according to age of onset have been described although these have not been consistently replicated. The majority of these studies(More)
OBJECTIVE To determine the effect of living with a depressed elderly individual on the mental health of the cohabitant carer. METHOD Case-control study comparing rates of psychiatric morbidity in cohabitants of depressed versus well elderly. SETTING Community sample. PARTICIPANTS 44 couples, one partner with AGECAT depression, and 44 couples, one(More)
BACKGROUND Exercise interventions to prevent dementia and delay cognitive decline have gained considerable attention in recent years. Human and animal studies have demonstrated that regular physical activity targets brain function by increasing cognitive reserve. There is also evidence of structural changes caused by exercise in preventing or delaying the(More)
BACKGROUND Epidemiological studies suggest an association between health factors and dementia. The impact of these factors on the cognitive performance of the elderly population is unclear. Possible correlates of poor cognitive performance in a community dwelling elderly Irish population were examined. METHODS Subjects were from a sample of individuals(More)