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Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula.
Cyanobacteria, or blue-green algae, are a rich source of novel bioactive secondary metabolites that have potential applications as antimicrobial or anticancer agents or useful probes in cell biologyExpand
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Chlamydia trachomatis serovar L2 can utilize exogenous lipoic acid through the action of the lipoic acid ligase LplA1.
Lipoic acid is an essential protein bound cofactor that is vital for the functioning of several important enzymes involved in central metabolism. Genomes of all sequenced chlamydiae show the presenceExpand
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The Secondary Metabolites and Biosynthetic Gene Clusters of Marine Cyanobacteria . Applications in Biotechnology
*For correspondence email bill.gerwick@oregonstate.edu Abstract Marine cyanobacteria have proven to be one of the most versatile marine producers of secondary metabolites. Many of these metabolitesExpand
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Microarray analysis of Shigella flexneri-infected epithelial cells identifies host factors important for apoptosis inhibition
BackgroundShigella flexneri inhibits apoptosis in infected epithelial cells. In order to understand the pro-survival effects induced by the bacteria, we utilized apoptosis-specific microarrays toExpand
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