Aisha Nalusaji

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Improved laboratory diagnosis is critical to reduce the burden of malaria in pregnancy. Peripheral blood smears appear less sensitive than Plasmodium falciparum histidine-rich protein 2-based rapid diagnostic tests (RDTs) for placental malaria infections in studies conducted at delivery. In this study, 81 women in Uganda in the second or third trimester of(More)
Data on efficacy of artemisinin-based combination therapy (ACT) to treat Plasmodium falciparum during pregnancy in sub-Saharan Africa is scarce. A recent open label, randomized controlled trial in Mbarara, Uganda demonstrated that artemether-lumefantrine (AL) is not inferior to quinine to treat uncomplicated malaria in pregnancy. Haemozoin can persist in(More)
Malaria is often considered a cause of adult sepsis in malaria endemic areas. However, diagnostic limitations can make distinction between malaria and other infections challenging. Therefore, the objective of this study was to determine the relative contribution of malaria to adult sepsis in south-western Uganda. Adult patients with sepsis were enrolled at(More)
Pregnant women are highly susceptible to malaria infection and disease, which frequently leads to placental para-sitemia, maternal and infant anemia, and low birth weight, all of which directly or indirectly increase the risk of maternal, fetal and infant death. 1, 2 The adverse effects of Plasmodium falciparum malaria in pregnancy are more marked in(More)
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