Aisha Khan

1Ivonne Hernandez Schulman
1Michael A. Bellio
1Stacey L Gorniak
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Following the success obtained with transplantation of fresh human islets under steroid-free immunosuppression, this trial evaluated the transplantation of islets that had undergone a period of in vitro culture and the potential of tumor necrosis factor (TNF-alpha) blockade to improve islet engraftment. Subjects included 16 patients with type 1 diabetes(More)
We address the problem of detecting and localizing cells in time lapse microscopy images during early stage embryo development. Our approach is based on a linear chain Markov model that estimates the number and location of cells at each time step. The state space for each time step is derived from a randomized ellipse fitting algorithm that attempts to find(More)
BACKGROUND Endothelial dysfunction, characterized by diminished endothelial progenitor cell (EPC) function and flow-mediated vasodilation (FMD), is a clinically significant feature of heart failure (HF). Mesenchymal stem cells (MSCs), which have pro-angiogenic properties, have the potential to restore endothelial function. Accordingly, we tested the(More)
Measurement of the proliferative behavior of human embry-onic cells in vitro is important to many biomedical applications ranging from basic biology research to advanced applications , such as determining embryo viability during in vitro fertilization (IVF) treatments. Automated prediction of the embryo viability, by tracking cell divisions up to the 4-cell(More)
Previous studies of fine motor control have focused on the ability of participants to match their grip force production to a visually provided template. We investigated differences exhibited in pinch force control during variable force production templates, including sine-, sawtooth-, and square-wave templates. Our results indicate that increased force(More)
Recently, it has been shown that early division patterns, such as cell division timing biomarkers, are crucial to predict human embryo viability. Precise and accurate measurement of these markers requires cell lineage analysis to identify normal and abnormal division patterns. However, current approaches to early-stage embryo analysis only focus on(More)
Although evidence has emerged regarding functional neural impairment of all four limbs with a diagnosis of type II diabetes (T2D), there is conflicting evidence regarding impairment in manual function with the disease. The purpose of the current study was to evaluate hand/fingertip function in T2D as compared to healthy age- and gender-matched controls. Ten(More)
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