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The feasibility problem for a system of linear inequalities can be converted into an unconstrained optimization problem using ideas from the ellipsoid method, which can be viewed as a very simple minimization technique for the resulting nonlinear function. Using more sophisticated algorithms, we develop and investigate more eecient methods, which lead to(More)
PURPOSE To investigate the effects of mycophenolate mofetil (MMF) on proliferation and mucin-5AC (MUC5AC) mRNA expression of normal human conjunctival goblet cells (CGCs) in vitro and to understand mechanisms of MMF in treatment of dry eye syndrome at molecular level. METHODS Purified human CGCs were treated with a series of graded concentrations of MMF(More)
Image degradation by loss of higher spatial frequencies causes form-deprivation myopia (FDM) in humans and animals, and cyclical illumination (flicker) at certain frequencies may prevent FDM. The molecular mechanisms underlying FDM and its prevention by flicker are poorly known. To understand them better, we have identified proteins that differ in amount in(More)
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