Ainsley J Newson

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Non-invasive prenatal diagnosis (NIPD) could significantly change the framework for testing and screening in pregnancy. This chapter reviews the ethical implications of this technology, including current issues in prenatal diagnosis, implications for informed consent, possible non-medical uses and options for regulation. The prospect of NIPD normalising(More)
BACKGROUND Personalized genomic risk information has the potential to motivate behaviour change and promote population health, but the success of this will depend upon effective risk communication strategies. OBJECTIVE To determine preferences for different graphical and written risk communication formats, and the delivery of genomic risk information(More)
OBJECTIVE Informed choice is a fundamental concept within prenatal care. The present study assessed the extent to which the introduction of non-invasive prenatal diagnosis (NIPD) of Down's syndrome may undermine the process of making informed choices to undergo prenatal testing or screening for Down's syndrome by altering the quality and quantity of(More)
Empirical evidence suggests that some health professionals believe consent procedures for the emerging technology of non-invasive prenatal diagnosis (NIPD) should become less rigorous than those currently used for invasive prenatal testing. In this paper, we consider the importance of informed consent and informed choice procedures for protecting autonomy(More)
Cascade testing or screening provides an important mechanism for identifying people at risk of a genetic condition. For some autosomal dominant conditions, such as familial hpercholesterolaemia (FH), identifying relatives allows for significant health-affecting interventions to be administered, which can extend a person's life expectancy significantly.(More)
This target article considers the ethical implications of providing prenatal diagnosis (PND) and antenatal screening services to detect fetal abnormalities in jurisdictions that prohibit abortion for these conditions. This unusual health policy context is common in the Latin American region. Congenital conditions are often untreated or under-treated in(More)
The water soluble benzodiazepine, midazolam, was compared with thiopentone as an intravenous induction agent in unpremedicated patients undergoing cystoscopy as out-patients. Induction time was longer with midazolam, though subsequent transition to halothane inhalation anaesthesia was smooth and uneventful. Both drugs had similar effects on the(More)
BACKGROUND Genetic testing of preimplantation embryos has been used for preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS). Microarray technology is being introduced in both these contexts, and whole genome sequencing of blastomeres is also expeted to become possible soon. The amount of extra information such tests will(More)
Recent scientific advances mean the widespread introduction of non-invasive prenatal diagnosis (NIPD) for chromosomal aneuploidies may be close at hand, raising the question of how NIPD should be introduced as part of antenatal care pathways for pregnant women. In this paper, the authors examine the ethical implications of three hypothetical models for(More)