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Metabolic markers in blood can separate prostate cancer from benign prostatic hyperplasia
Background:An individualised risk-stratified screening for prostate cancer (PCa) would select the patients who will benefit from further investigations as well as therapy. Current detection methodsExpand
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Presence of TMPRSS2-ERG is associated with alterations of the metabolic profile in human prostate cancer
TMPRSS2-ERG has been proposed to be a prognostic marker for prostate cancer. The aim of this study was to identify changes in metabolism, genes and biochemical recurrence related to TMPRSS2-ERG byExpand
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Trace element status in patients with type 2 diabetes in Norway: The HUNT3 Survey.
Several epidemiological studies have indicated that a number of trace elements may play a role in type 2 diabetes (T2D). We investigated the association between prevalent T2D and the concentrationsExpand
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Trace elements in early phase type 2 diabetes mellitus-A population-based study. The HUNT study in Norway.
Differences in trace elements levels between individuals with type 2 diabetes and controls have been reported in several studies in various body fluids and tissues, but results have beenExpand
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A novel non-canonical Wnt signature for prostate cancer aggressiveness
Activation of the Canonical Wnt pathway (CWP) has been linked to advanced and metastatic prostate cancer, whereas the Wnt5a-induced non-canonical Wnt pathway (NCWP) has been associated with both goodExpand
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Real‐time measurement of hyperpolarized lactate production and efflux as a biomarker of tumor aggressiveness in an MR compatible 3D cell culture bioreactor
We have developed a 3D cell/tissue culture bioreactor compatible with hyperpolarized (HP) 13C MR and interrogated HP [1‐13C]lactate production and efflux in human renal cell carcinoma (RCC) cells.Expand
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Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy
Background:Robust biomarkers that identify prostate cancer patients with high risk of recurrence will improve personalised cancer care. In this study, we investigated whether tissue metabolitesExpand
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Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy
This corrects the article DOI: 10.1038/bjc.2017.346
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Ex vivo metabolic fingerprinting identifies biomarkers predictive 1 of prostate cancer recurrence following radical prostatectomy 2 Running title : Metabolites in prostate cancer predict recurrence 3
Peder R. Braadland, Guro Giskeødegård, Elise Sandsmark, Helena Bertilsson, Leslie R. 4 Euceda, Ailin F. Hansen, Ingrid J. Guldvik, Kirsten Selnæs, Helene H. Grytli, Betina Katz, 5 Aud Svindland, ToneExpand