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Gefitinib and EGFR Gene Copy Number Aberrations in Esophageal Cancer.

• Russell David Petty, Åsa Dahle-Smith, +19 authors Zosia H. Miedzybrodzka
• Journal of clinical oncology : official journal…
• 2017

Purpose The Cancer Esophagus Gefitinib trial demonstrated improved progression-free survival with the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib relative to placebo… (More)

A Rapid Method of Screening for N-Acetyltransferase (NAT2) Phenotype by Use of the WAVE DNA Fragment Analysis System

• Aileen Osborne, Christine Elizabeth Bell, F. Hank Grant, Finlay D Dick, Anthony Seaton, Neva E. Haites
• Biochemical Genetics
• 2003

N-Acetyltransferase 2 (NAT2) is involved in Phase II biotransformation of a variety of toxicants. Polymorphisms in the NAT2gene result in a slow acetylator phenotype, which has been associated with… (More)

A case-control study of Parkinson's disease and tobacco use: gene-tobacco interactions.

• Giuseppe de Palma, Finlay D Dick, +8 authors Antonio Mutti
• Movement disorders : official journal of the…
• 2010

A case-control study of genetic, environmental, and occupational risk factors for Parkinson's disease (PD) was carried out in five European countries (Italy, Malta, Romania, Scotland, and Sweden) to… (More)

Epidermal Growth Factor (EGFR) copy number aberrations in esophageal and gastro-esophageal junctional carcinoma

• Åsa Dahle-Smith, David Stevenson, +8 authors Zosia H. Miedzybrodzka
• Molecular Cytogenetics
• 2015

Clinical trials of agents targeting epidermal growth factor receptor (EGFR) in esophageal carcinoma (EC) have indicated a minority subgroup responsive to anti-EGFR therapies. Other investigations… (More)

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