Aijun Xu

Yuke Tian2
Bin Liu1
2Yuke Tian
1Bin Liu
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BACKGROUND Mitochondria are critical to cardiac injury during reperfusion as a result of damage sustained during ischemia, including the loss of bcl-2. We asked if bcl-2 depletion not only leads to selective permeation of the outer mitochondrial membrane (MOMP) favoring cytochrome c release and programmed cell death, but also favors opening of the(More)
Descending nociceptive modulation from the supraspinal structures plays an important role in cancer-induced bone pain (CIBP). Rostral ventromedial medulla (RVM) is a critical component of descending nociceptive facilitation circuitry, but so far the mechanisms are poorly known. In this study, we investigated the role of RVM glial activation in the(More)
Studies have shown that single-prolonged stress (SPS) can induce the apoptotic process in the amygdala. In the present study, we aimed to detect expression of phosphorylated p44/42 extracellular signal-regulated kinase (pERK1/2) and apoptosis-related Bax and Bcl-2 and apoptotic cell death in the amygdala region in SPS rats as well as the relation between(More)
The effects of intracerebroventricular (icv) agonists and antagonists of N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors on the general anesthesia of propofol were studied. A total of 144 Kunming mice, male and female with body mass of (22±3) g, were used. Part One of the Experiment: a total of 104(More)
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