• Publications
  • Influence
Regulation of Nrf2 transactivation domain activity by p160 RAC3/SRC3 and other nuclear co-regulators.
  • Wen Lin, G. Shen, +5 authors A. Kong
  • Biology, Medicine
  • Journal of biochemistry and molecular biology
  • 31 May 2006
Transcription factor NF-E2-related factor 2 (Nrf2) regulates the induction of Phase II detoxifying enzymes and antioxidant enzymes in response to many cancer chemopreventive compounds. In this study,Expand
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Chronic arsenic poisoning from burning high-arsenic-containing coal in Guizhou, China.
Arsenic is an environmental hazard and the reduction of drinking water arsenic levels is under consideration. People are exposed to arsenic not only through drinking water but also throughExpand
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Unventilated Indoor Coal-Fired Stoves in Guizhou Province, China: Cellular and Genetic Damage in Villagers Exposed to Arsenic in Food and Air
Background Inorganic arsenic (iAs) is a well-known human carcinogen recognized by the World Health Organization and the International Agency for Research on Cancer. Currently, most iAs studies inExpand
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Chronic arsenic poisoning from burning high-arsenic-containing coal in Guizhou, China.
Arsenic is an environmental hazard and the reduction of drinking water arsenic levels is under consideration. People are exposed to arsenic not only through drinking water but also throughExpand
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The lncRNA MALAT1, acting through HIF-1α stabilization, enhances arsenite-induced glycolysis in human hepatic L-02 cells.
Accelerated glycolysis, a common process in tumor cells called the Warburg effect, is associated with various biological phenomena. However, the role of glycolysis induced by arsenite, aExpand
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A MALAT1/HIF-2α feedback loop contributes to arsenite carcinogenesis
Arsenic is well established as a human carcinogen, but the molecular mechanisms leading to arsenic-induced carcinogenesis are complex and elusive. It is also not known if lncRNAs are involved inExpand
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Exosomal circRNA_100284 from arsenite-transformed cells, via microRNA-217 regulation of EZH2, is involved in the malignant transformation of human hepatic cells by accelerating the cell cycle and
Intercellular communication between malignant cells and neighboring nonmalignant cells is involved in carcinogenesis. In the progression of carcinogenesis, exosomes are messengers for intercellularExpand
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Development of a sensitive competitive indirect ELISA method for determination of ochratoxin A levels in cereals originating from Nanjing, China
Abstract A monoclonal antibody against ochratoxin A (OTA) was produced and a simple, rapid and reliable competitive indirect ELISA (ci-ELISA) for detection of OTA was developed. The 50% inhibitoryExpand
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The acquisition of cancer stem cell-like properties and neoplastic transformation of human keratinocytes induced by arsenite involves epigenetic silencing of let-7c via Ras/NF-κB.
Exposure of humans to inorganic arsenic can cause skin cancer. The acquisition of cancer stem cell-like properties is involved in the initiation of some cancers, and there are changes in let-7 levelsExpand
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A mitochondria-mediated apoptotic pathway induced by deoxynivalenol in human colon cancer cells.
Deoxynivalenol (DON), known colloquially as "vomitoxin", is a pathogenic mycotoxin produced by Fusarium fungi. Human food poisoning outbreaks, with nausea, diarrhea, and vomiting as primary symptoms,Expand
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