Aifric O'Sullivan

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Breast milk delivers nutrition and protection to the developing infant. There has been considerable research on the high-molecular-weight milk components; however, low-molecular-weight metabolites have received less attention. To determine the effect of maternal phenotype and diet on the human milk metabolome, milk collected at day 90 postpartum from 52(More)
The effects of three preslaughter diets on heifer beef quality were investigated. Heifers (n = 45) were divided into three groups and fed for ad libitum consumption either maize silage, grass silage, or a 50:50 mixture of maize silage and grass silage. Meat quality was determined by measuring color, lipid oxidation, alpha-tocopherol levels, and fatty acid(More)
The objective of this study was to determine the effects of hot-boning, low voltage electrical stimulation (ES) and chilling temperature on the tenderness of bovine M. longissimus dorsi (LD) and M. semimembranosus (SM) muscles. LD (n=32) and SM (n=32) muscles were subjected to different post-mortem treatments; hot-boning (before 90min post-mortem),(More)
The objective of this study was to evaluate the importance of proteolysis and sarcomere length in determining the tenderness of bovine M. longissimus dorsi (LD) muscle over a 21-day period. This was done by altering the pre-rigor glycolytic behaviour of hot-boned LD muscles using different early post-mortem temperature regimes. Hot-boned LD muscles (n=8)(More)
The aim of this study was to monitor the effects of the alteration of the pre-rigor environment of the bovine LD muscle using controlled temperature regimes in order to gain an insight into the early post-mortem pH/temperature/time interactions which are important from the point of view of tenderness and to identify possible reasons for inconsistencies in(More)
BACKGROUND It has been suggested that metabolomics could play a role in dietary assessment and identification of novel biomarkers of dietary intake. OBJECTIVE This study examined the link between habitual dietary patterns and metabolomic profiles. DESIGN A total of 160 volunteers participated in a double-blind, randomized, placebo-controlled dietary(More)
Epidemiological research has indicated a relationship between infant formula feeding and increased risk of chronic diseases later in life including obesity, type-2 diabetes, and cardiovascular disease. The present study used an infant rhesus monkey model to compare the comprehensive metabolic implications of formula- and breast-feeding practices using NMR(More)
This study was undertaken to investigate physiological adaptation with two endurance-training periods differing in intensity distribution. In a randomized crossover fashion, separated by 4 wk of detraining, 12 male cyclists completed two 6-wk training periods: 1) a polarized model [6.4 (±1.4 SD) h/wk; 80%, 0%, and 20% of training time in low-, moderate-,(More)
Continental Limousin and Charolais crossbred steers (n=66) were assigned to one of six diets: (1) high herbage allowance (18 kg grass dry matter), zero concentrate (HH0C), (2) high herbage allowance and 2.5 kg concentrate (HHLC), (3) high herbage allowance and 5 kg concentrate (HHHC), (4) low herbage allowance (6 kg grass DM) and 5 kg concentrate (LHHC),(More)
OBJECTIVES Rhesus macaque monkeys are widely used as models for human physiology and behavior. They are particularly suited for studies on infant nutrition and metabolism; however, few studies have directly compared their metabolic or microbiological phenotypes. The aim of the present study was to compare the metabolomic profiles and microbiome of milk from(More)