Aida Ebrahimi

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S1. Geometry dependence of circuit components: a) Geometric Capacitance )) : For a parallel plate system, the geometric (dielectric) capacitance is given by where is the area of the electrodes, permittivity of the medium separating the electrodes and the separation between the electrodes. This results from the solution of Poisson equation and is determined(More)
Label-free, rapid detection of biomolecules in microliter volumes of highly diluted solutions (sub-femtomolar) is of essential importance for numerous applications in medical diagnostics, food safety, and chem-bio sensing for homeland security. At ultra-low concentrations, regardless of the sensitivity of the detection approach, the sensor response time is(More)
Label-free, rapid detection of biomolecules in microliter volumes of highly diluted solutions (subfemtomolar) is of essential importance for numerous applications in medical diagnostics, food safety, and chem-bio sensing for homeland security. At ultra-low concentrations, regardless of the sensitivity of the detection approach, the sensor response time is(More)
a School of Electrical and Computer Engineering, Purdue University, West Lafayette, IN 47907, USA b Birck Nanotechnology Center, Purdue University, West Lafayette, IN 47907, USA c School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA d Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801,(More)
Direct antibiotic susceptibility tests (AST) are essential for rapid detection of bacterial infection and administration of appropriate antibiotics. Conventional AST systems are usually slow as they rely on cell growth for an indirect assessment of antibiotics' effectiveness. Therefore, a faster method is desirable, especially for emergency cases. In this(More)
  • Aida Ebrahimi, Muhammad Ashraful Alam
  • Proceedings of the National Academy of Sciences…
  • 2016
Bacteria cells use osmoregulatory proteins as emergency valves to respond to changes in the osmotic pressure of their external environment. The existence of these emergency valves has been known since the 1960s, but they have never been used as the basis of a viability assay to tell dead bacteria cells apart from live ones. In this paper, we show that(More)
Low cost, portable sensors can transform health care by bringing easily available diagnostic devices to low and middle income population, particularly in developing countries. Sample preparation, analyte handling and labeling are primary cost concerns for traditional lab-based diagnostic systems. Lab-on-a-chip (LoC) platforms based on droplet-based(More)
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