Ahmed Refaat

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Improvement of the dissolution behavior of poorly water soluble tadalafil using solid dispersion technique was investigated. Polyvinylpyrollidone (PVP) was used to prepare solid dispersions (SDs) based on different ratios; 1:1 (SD1,), 1:2 (SD2,), 1:3 (SD3), 1:4 (SD4,) respectively. Tadalafil/PVP/Avicel® in a ratio of 1:2:2 respectively (SD5) was also(More)
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