Agustín Mayo-Iscar

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PURPOSE To asses risk factors of proliferative vitreoretinopathy (PVR) and a model for predicting it. METHODS Observational, case-control. 335 patients with non-complicated retinal detachment (RD) were included: 134 developed PVR (Cases); 201 patients did not (Controls). Risk factors for PVR were identified by multivariate analysis. Influence of variables(More)
Two key questions in Clustering problems are how to determine the number of groups properly and measure the strength of group-assignments. These questions are specially involved when the presence of certain fraction of outlying data is also expected. Any answer to these two key questions should depend on the assumed probabilisticmodel, the allowed group(More)
The presence of clusters in a data set is sometimes due to the existence of certain relations among the measured variables which vary depending on some hidden factors. In these cases, observations could be grouped in a natural way around linear and nonlinear structures and, thus, the problem of doing robust clustering around linear affine subspaces has(More)
PURPOSE To identify the clinical characteristics of patients developing retinal shortening due to intraretinal PVR. METHODS Observational and retrospective cohort study on 110 PVR patients operated on between 2000 and 2001. During surgery, after removing epiretinal membranes and ruling out the presence of subretinal membranes, a perfluorocarbon liquid was(More)
Recent preclinical evidence has suggested that Ewing Sarcoma (ES) bearing EWSR1-ETS fusions could be particularly sensitive to PARP inhibitors (PARPinh) in combination with DNA damage repair (DDR) agents. Trabectedin is an antitumoral agent that modulates EWSR1-FLI1 transcriptional functions, causing DNA damage. Interestingly, PARP1 is also a(More)
PURPOSE Adverse environmental conditions elicit dry eye (DE)-related signs and symptoms. The purpose of this work is to determine whether these conditions can alter a normal-to-borderline ocular surface in subjects with DE symptoms. METHODS Ten minimally symptomatic contact lens (CL)-wearing subjects were exposed, without (WO-) and with (W-)CLs, to a(More)
PURPOSE To compare the cellularity of vitreous samples obtained from patients with rhegmatogenous retinal detachment complicated by proliferative vitreoretinopathy (PVR) and from patients with uncomplicated rhegmatogenous retinal detachment (RD) to detect possible variations in cellularity over time. METHODS One hundred and twenty-five vitreous specimens(More)
PURPOSE To determine the effects of intravitreal atropine on scleral growth in the form-deprived chick as an experimental model of myopia. METHODS Five groups of five chicks were studied from day 0-12 post-hatching. One group remained untreated (C), and four were form-deprived by monocular light diffusers to induce myopia. Two groups (RL and A) wore(More)
The aim of the present study was to assess the changes in flow patterns of forearm arteries produced by excision of the radial artery when harvesting the radial forearm flap. A prospective study using color duplex imaging for quantitative flow measurements was accomplished in 11 patients. After raising the radial flap, the forearm flow tended to increase(More)