Agustín Martínez-Ibargüen

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One of the most common causes of mortality and morbidity in children is perinatal hypoxia-ischemia (HI). In spite of the advances in neonatology, its incidence is not diminishing, generating a pediatric population that will require an extended amount of chronic care throughout their lifetime. For this reason, new and more effective neuroprotective(More)
CONCLUSIONS 1. The principle of bilateral symmetry depends on the chordal cartilage that is the keystone in cranial base ossification in rats and humans, due to its anatomical situation and for the production of the chordin protein that regulates the bone morphogenetic protein BMP-7. 2. In humans and in rats, foramen lacerum closure follows a line of(More)
INTRODUCTION Inflammatory myofibroblastic tumor (IMFT) of the temporal bone is an unusual but distinct clinicopathologic entity. CASE REPORT We report the case of a 75-year-old patient with an IMFT located in the temporal bone. Symptoms included VI, X, XI, and XII cranial nerves palsies. Computed tomography and magnetic resonance images are described. The(More)
Maturation of the auditory pathway is dependent on the central nervous system myelination and it can be affected by pathologies such as neonatal hypoxic ischemic (HI) encephalopathy. Our aim was to evaluate the functional integrity of the auditory pathway and to visualize, by histological and cellular methods, the damage to the brainstem using a neonatal(More)
The perinatal brainstem is known to be very vulnerable to hypoxic–ischemic events which can lead to deafness, swallowing dysfunction, and defective respiratory control. The aim of the present work was to evaluate the potential neuroprotective effects of nicotine, melatonin, resveratrol, and docosahexaenoic acid on the expression of a panel of genes in the(More)
Auditory impairments are considered to be one of the most frequent neurosensorial problems in human. The normal development and myelination of the auditory system can be impaired by certain pathological conditions such as viral infections, hyperbilirubinemia, meningitis, fetal distress and perinatal asphyxia. The early detection of this hearing loss can be(More)
CONCLUSIONS The normal nasal lymphatic drainage runs via the facial vessels into the neck lymphatic nodes of levels I-II and this drainage pattern was found in our patients with sinonasal tumors. We found only one true-positive sentinel lymph node (SLN). Our pathological material was very limited and so further investigations are required before any valid(More)
CONCLUSIONS Human-rat geniculate ganglion (GG) have multiple origins: (1) An initial proximity (20 μm) to the endocranial foramen of the IAM, suggests neural crest induction; and (2) The influence of epibranchial placodes: the tensor tympani muscle (TTM) and the otic apical coil. OBJECTIVES This study was undertaken to determine the comparative(More)
OBJECTIVES We tried to assess the relationship between nasal resistance measured by rhinomanometry and the pressure used in CPAP. DESIGN Retrospective medical case series review, January 2004 to December 2014. SETTING Tertiary care academic medical centre. PARTICIPANTS Thirty-eight patients (m = 56.55 years; male = 90.5%) with CPAP settings ≤8 and 39(More)