Agustín De Dios Hernández

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Synchronization in parallel programs is a major performance bottleneck. Shared data is protected by locks and a lot of time is spent in the competition arising at the lock hand-off. In this period of time, a large amount of traffic is targeted to the line holding the lock variable. In order to be serialized, the requests to the same cache line can either be(More)
In this paper we put forward a design for a multicomputer system based on a network of workstations which we call COMA-BC. It has a common address space in which a shared variables programming model can be used. The management of the shared address space is performed in a similar way to that in existing multiprocessor COMA systems. To be exact, the shared(More)
Synchronization in parallel programs is a major performance bottleneck in multiprocessor systems. Shared data is protected by locks and a lot of time is spent on the competition arising at the lock hand-off. In order to be serialized, requests to the same cache line can either be bounced (NACKed) or buffered in the coherence controller. In this paper, we(More)
The protozoan parasite Cryptosporidium parvum causes waterborne diseases worldwide. There is no effective therapy for C. parvum infection. The parasite depends mainly on glycolysis for energy production. Lactate dehydrogenase is a major regulator of glycolysis. This paper describes the biochemical characterization of C. parvum lactate dehydrogenase and high(More)
Amine fungicides are widely used as crop protectants. Their success is believed to be related to their ability to inhibit postlanosterol sterol biosynthesis in fungi, in particular sterol-Δ(8),Δ(7)-isomerases and sterol-Δ(14)-reductases, with a concomitant accumulation of toxic abnormal sterols. However, their actual cellular effects and mechanisms of death(More)
In this paper we discuss the behavior of the replacement mechanism of well-known COMA protocols applied to a loosely-coupled multicomputer system sharing a common bus. We also present VSR-COMA, a COMA protocol that uses an advanced replacement mechanism in order to select the destination node of a replacement transaction without introducing penalties due to(More)
We report herein results of a study performed in the Balearic Islands which had the following goals: 1) Determine the proportion of pregnant or non-pregnant women planning pregnancy, who would choose to undergo a screening test for Fragile X Syndrome (FXS), if it is accompanied by the appropriate information; 2) Assess satisfaction and any increase in(More)
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