Agnieszka Sciubisz

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Catecholamines act via dopaminergic-, and adrenergic receptors, and are involved in a variety of regulatory systems. They take part in regulation of the response to stress, psychomotor activity, emotional processes, learning, sleep and memory. Due to many catecholaminergic pathways, and a wide range of functions they are involved in, both in the central(More)
A C-terminal analog of the hexapeptide orphanin FQ/nociceptin-(1-6), [Ala(6)]-orphanin FQ/nociceptin-(1-6), and a pentapeptide orphanin FQ/nociceptin-(1-5) were tested in vivo for their analgesic/hyperalgesic activity in the hot-plate test with rats. Replacement of the C-terminal glycine by L-alanine (Phe-Gly-Gly-Phe-Thr-Ala) in orphanin FQ/nociceptin-(1-6)(More)
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