Agnieszka Rusińska

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INTRODUCTION The aim of the study is to determine whether serum concentrations of interleukin (IL)-1and IL-6 correlate with indices of bone mineral metabolism in children with idiopathic osteoporosis and osteopenia. MATERIAL/METHODS The study comprised 62 patients aged 6-18 years (20 with idiopathic osteoporosis, 22 with idiopathic osteopenia, and 20(More)
OBJECTIVE To determine whether the serum concentration of insulin-like growth factor I (IGF-I) correlates with the occurrence of idiopathic osteoporosis in children, and whether serum levels of IGF-I correlate with selected bone metabolism markers in patients with osteoporosis. METHODS The study comprised 24 patients aged 7-18 years, including 12 with(More)
BACKGROUND The aim of the study was to carry out a comprehensive analysis of determinants of multiple bone fractures in children with regard to densitometric indices and markers of bone metabolism. MATERIAL AND METHODS The study involved 112 children aged 5-18 years, including 81 patients with a history of at least 3 bone fractures and 31 healthy patients(More)
Angelman syndrome is a genetically inherited syndrome with severe retardation of psychomotor development and speech disturbances, usually accompanied by epilepsy, typical dysmorphic features, and some skeletal symptoms. The aim of the current report is to present new skeletal symptoms which may occur in the course of AS, based on a case report of an(More)
The study was carried out in 20 children aged 6-18 years receiving long-term corticosteroid treatment for nephrotic syndrome. In these children densitometric evaluation of bone by DEXA method (total body and spine) and ultrasound measurement of heel were performed. Moreover, basic parameters of calcium-phosphate metabolism were determined. Osteoporosis and(More)
UNLABELLED Fractures of long bone and ribs in the neonatal period may be expression of genetic disturbances of collagen type I production. The aim of the study was to present clinical symptoms, results of radiological, biochemical and densitometric examinations in 11 newborns with osteogenesis imperfecta type III. METHODS In all children accurate medical(More)
UNLABELLED The aim of the study is proteomic analysis of the plasma profile in children with recurrent bone fractures. The study involved 16 children: 6 patients with recurrent low-energy fractures and normal bone mass and 10 with osteogenesis imperfecta. In the analysis of the protein profile, the two-dimensional protein electrophoresis was used (Ettan(More)
The paper presents current literature review on the clinical features and possible etiopathogenetic factors in idiopathic osteoporosis and osteopenia in children and adolescents. Genetic and environmental factors determining bone mass growth are included. The effect of cytokines and hormones in the regulation of bone remodelling has been discussed in(More)
In the paper the analysis of the clinical course of sepsis caused by Gram negative bacteria in 45 children hospitalized in Institute of Pediatrics at Medical University of Lodz in 1995-1998 was performed. Sepsis was diagnosed by bacterial analysis of blood serum, urine, stool and the ending of central venous tract. The most often etiological factor of(More)
INTRODUCTION Only few publications concern the influence of the vitamin D and calcium consumption on the bone mineralization in the developmental age. AIM OF THE STUDY The aim of the study was the analysis of the vitamin D and calcium diet supply in relation to the bone status assessed with Quantitative Ultrasound (QUS) in growing children. MATERIAL AND(More)