Agnieszka Czopik Holt

Publications3
h-index3
Citations7,731
Highly Influential Citations274
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Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
TLDR
It is shown that mammalian TLR3 recognizes dsRNA, and that activation of the receptor induces the activation of NF-κB and the production of type I interferons (IFNs).
View on Springer
Toll-like receptors control activation of adaptive immune responses
TLDR
It is shown that MyD88-deficient mice have a profound defect in the activation of antigen-specific T helper type 1 (TH1) but not TH2 immune responses, suggesting that distinct pathways of the innate immune system control activation of the two effector arms of adaptive immunity.
View on Nature
Recognition of CpG DNA is mediated by signaling pathways dependent on the adaptor protein MyD88
View on Elsevier