Agneta Bergström

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We used the validated chronic mild stress (CMS) paradigm to induce anhedonia, a core symptom of major depression, in rats. Thirty percent of animals exposed to CMS are resistant to the development of anhedonia, whereas the remaining are responsive, CMS resilient and CMS sensitive, respectively. We used in situ hybridization to elucidate the molecular(More)
The current antidepressant drugs are ineffective in 30 to 40% of the treated patients; hence, the pathophysiology of the disease needs to be further elucidated. We used the chronic mild stress (CMS) paradigm to induce anhedonia, a core symptom of major depression, in rats. A fraction of the animals exposed to CMS is resistant to the development of(More)
We have explored a novel method to find textual relations in electronic documents using genetic programming and semantic networks. This can be used for enhancing information retrieval and simplifying user interfaces. The automatic extraction of relations from text enables easier updating of electronic dictionaries and may reduce interface area both for(More)
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