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Hepatitis B virus suppresses toll‐like receptor–mediated innate immune responses in murine parenchymal and nonparenchymal liver cells
We have previously shown that Toll‐like receptor (TLR)‐activated murine nonparenchymal liver cells [(NPC); Kupffer cells (KC), liver sinusoidal endothelial cells (LSEC)] can suppress hepatitis BExpand
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Toll‐like receptor‐induced innate immune responses in non‐parenchymal liver cells are cell type‐specific
Little is known of how the Toll‐like receptor (TLR) system can modulate the function of non‐parenchymal liver cells (NPC) as a major component of the innate and adaptive immune system of the liver.Expand
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Treatment with the NF-κB inhibitor bortezomib leads to suppression of proregenerative cytokines and significant mortality after liver resection
Introduction: After liver resections or transplantations ischemia/reperfusion injury or inflammatory processes that are mediated through activation of the transcription factor NF-κB lead toExpand