Agne Kulyté

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BACKGROUND A majority of bacterial genes belong to tight clusters and operons, which complicates gene functional studies using conventional knock-out methods. Antisense agents can down-regulate the expression of genes without disrupting the genome because they bind mRNA and block its expression. However, it is unclear how antisense inhibition affects(More)
Background: A majority of bacterial genes belong to tight clusters and operons, which complicates gene functional studies using conventional knockout methods. Antisense agents can down-regulate the expression of genes without disrupting the genome because they bind mRNA and block its expression. However, it is unclear how antisense inhibition affects(More)
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