Agata Kochman

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Lipopolysaccharide (LPS), the major component of the outer membrane of Gram-negative bacteria, contains the O-polysaccharide, which is important to classify bacteria into different O-serological types within species. The O-polysaccharides of serotypes O24 and O56 of E. coli contain sialic acid in their structures, already established in our previous(More)
REVIEWS Parkinson's disease is a progressive neurode− generative disorder affecting about 2% of the po− pulation above 65 years [1]. The clinical presenta− tion of PD includes bradykinesia, resting tremors, rigidity, and later loss of postural reflexes [2]. Hi− stopathological findings in PD include progressive dysfunction and degeneration of the(More)
In our search for novel, low-toxic, cell-penetrable and neuroprotective antioxidants, we have designed a number of novel N-propargylamine derivatives of nitroxyl, named "JSAKs". The reactivity and antioxidative potency of two selected JSAKs and their parent nitroxyl against reactive oxygen species (ROS) were examined in vitro, in a cell-free(More)
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