Afzal Khan

Learn More
Imidazole-based structures of p38 inhibitors served as a starting point for the design of JNK3 inhibitors. Construction of a 6,7-dihydro-5H-pyrrolo[1,2-a]imidazole scaffold led to the synthesis of the (S)-enantiomers, which exhibited p38/JNK3 IC50 ratio of up to 10 and were up to 20 times more potent inhibitors of JNK3 than the relevant (R)-enantiomers. The(More)
An integrated program of research aimed at understanding wing flexibility and its implications for flight in insects is described. The experimental component of the research involves quantitative, high-speed videogrammetry of insects in free flight along with measurements of the mass and structural properties of the insect body and wings. The computational(More)
(2015) Templated polymerizations on solid supports mediated by complementary nucleoside interactions. Polymer Chemistry. which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed. A note on versions: The version presented in WRAP is the published version, or, version of record, and(More)
Gait analysis is a complex process since it involves tracking motion with high degrees of freedom. It has seen a lot of development in recent years with approaches changing from Markerbased to Markerless systems. This paper presents a new approach for gait analysis that is based on Markerless human motion capture using Microsoft's popular gaming console(More)
This paper uses a quarter model of an automobile having passive and semiactive suspension systems to develop a scheme for an optimal suspension controller. Semi-active suspension is preferred over passive and active suspensions with regard to optimum performance within the constraints of weight and operational cost. A fuzzy logic controller is incorporated(More)
Background: Endophytic fungi are known plant symbionts. They produce a variety of beneficial metabolites for plant growth and survival, as well as defend their hosts from attack of certain pathogens. Coastal dunes are nutrient deficient and offer harsh, saline environment for the existing flora and fauna. Endophytic fungi may play an important role in plant(More)
  • 1