Afshineh Latifynia

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BACKGROUND Leishmania is a significant health problem in many parts of the world. Tumor necrosis factor (TNF) plays an essential role in Leishmania major infections. OBJECTIVE To study the pro-inflammatory cytokines and antioxidants in four groups of cutaneous leishmaniasis patients. METHODS 39 patients were divided into four groups of: 1) active (acute(More)
Leishmania parasites cause a spectrum of diseases that afflict the populations of 88 countries around the world and all attempts to control leishmaniasis have failed. It seems that preparing a vaccine may be the final solution. The aim of this study was to determine various Leishmania (L.) major antigens vaccine candidates and effects of the vaccine on(More)
BACKGROUND Fasting during Ramadan represent one of the five pillars of the Islamic religion. So it is important to know the effect of this kind of fasting on people's life especially on their health. The purpose of this study was to show the effect of fasting during Ramadan on circulating immune complex (CIC) level and immune system. METHODS The CIC(More)
BACKGROUND Fasting during the month of Ramadan is one of the essential religious practices of Muslims. The aim of this study was to evaluate opsonisation, phagocytosis, and nitroblue tetrazolium (NBT) reduction by white blood cells in normal, healthy, male subjects under non-fasting (before Ramadan) and fasting (after Ramadan) conditions. METHODS In this(More)
OBJECTIVE The aim of this study was to carry out experiments further to our previous new formulation to modify the Leishmania major antigen that had satisfactory results previously. METHODS In this study we made a preliminary, new vaccine with the same methodology and selected two injection doses (100&200 μg/o.1 mL), three injection Groups: Leishmania(More)
BACKGROUND The aim of this study was to investigate the effects of Ramadan fasting on neutrophil's respiratory burst and circulating immune complex (CIC) level. METHODS The effects of Ramadan fasting on neutrophil's respiratory burst and CIC was studied in 21 normal young fasting Muslim individuals using standardized chemiluminescence and poly ethylene(More)
BACKGROUND/PURPOSE Leishmaniasis is currently a threat in 80 countries around the world, and cutaneous Leishmaniasis accounts for more than 5% of new cases. It is a problematic disease in Iran, and preparing a protective vaccine has been a major goal of medical investigations. The objective of this study was to compare the protective effects of a cocktail(More)
BACKGROUND Iran is considered as one of the countries which are located in high radiation area. Ramssar contains natural radioactive sources (Uranium-238) that can produce Radium-226 with high solubility and Radon gas with ability to fuse in dirt, soil, and water in its decay chain. Radioactive rays can produce free radicals with a short life time but high(More)
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