Learn More
In a previous paper we showed that the treatment of severe tetanus neonatorum by means of total paralysis and intermittent positive-pressure respiration (I.P.P.R.) represents a real therapeutic advance (Wright, Sykes, Jackson, Mann and Adams, 1961), and this has since been confirmed in Cape Town by Smythe (1963). Mortality rates of over 80% on conservative(More)
BACKGROUND Indeterminate results are a recognised limitation of interferon-γ release assays (IGRA) in the diagnosis of latent tuberculosis (TB) infection (LTBI) and TB disease, especially in children. We investigated whether age and common co-morbidities were associated with IGRA performance in an unselected cohort of resettled refugees. METHODS A(More)
BACKGROUND Diagnosis of latent tuberculosis infection (LTBI) is a cornerstone of the health assessment of resettled high incidence populations, particularly in children. Two blood-based interferon gamma release assays (IGRAs), T-SPOT.TB and QFT-Gold in-tube (QFT-GIT), have greater sensitivity and specificity than the tuberculin skin test (TST), but their(More)
The effect of standardized chest physiotherapy and hyperinflation on the blood gases of neonates being treated for tetanus by intermittent positive pressure respiration was investigated. It was found that physiotherapy and suction to remove secretions did not improve oxygen pressures but produced a small drop in both Paco., and Pao2. This was associated(More)
Measles-associated pneumonia, which was severe enough to require mechanical ventilation, caused a mortality of 64%. The main indications for special respiratory care were severe infection and hypoxaemia. Complications of the disease occurred in 78% of the patients. The commonest were anaemia, enteritis and cardiac failure, and they contributed to the grave(More)