Aeilke Brenner

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We surveyed neuro-oncologists regarding patients treated with temozolomide for at least 12 cycles or 12 months. Patients receiving first-line temozolomide for a median 13 cycles had a median progression-free survival (PFS) of 14 months. Patients with recurrent disease receiving a median 14 cycles had a median PFS of 15.5 months. A small percentage of(More)
Between 1976 and 1982 336 patients with an age range from several days to 65 years, were treated by ventriculo-atrial or peritoneal shunt, because of internal hydrocephalus of different origins. Regular computerized tomographies demonstrated slit-ventricles in 36 patients. Twenty-eight patients were free of complaints. In 8 patients there were symptoms like(More)
One hundred patients were submitted to a prospective, comparative study of metrizamide myelography and discography. In the 32 patients with cervical myelopathy discography yielded no additional information and was thus abandoned. The 68 patients with radiculopathy disease the following results were obtained: In view of the agreement between clinical and(More)
Congenital, spinal, epidural cysts are rare causes of transverse or radicular spinal lesions. Usually these cysts are located in the thoracal region, are oblong-shaped, and extend over several segments dorsally to the cord. Frequently, they cause no symptoms for years. They are fairly accessible to diagnostics by modern neuro-imaging methods. We report on a(More)
Neurocutaneous melanosis is often associated with melanoma of the central nervous system. Due to the inconspicuously looking cutaneous melanosis additional examinations are often not performed. We describe a patient with cutaneous melanosis who presented with neurological symptoms due to a large primary meningeal melanoma. The diagnosis of neurocutaneous(More)
This paper reports on the respective diagnostic values of myelography with water-soluble contrast media and diskography in a study of 100 patients examined between 1979 and 1981 and operated on because of cervical disk disease. The results of the study led to a change of the diagnostic procedures formerly applied in radicular syndromes (i.e., diskography,(More)
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