Adriano Piluso

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The measurement of bone mass, a reliable predictor of osteoporotic fractures, in obese subjects has yielded conflicting results and bone mass has been reported to be elevated, normal or decreased. These observations indicate that factors other than body weight may be involved in the less risk for osteoporosis in obese subjects. In order to clarify the role(More)
Several reports indicate higher endothelin-1 (ET-1) levels in patients with non insulin dependent diabetes mellitus (NIDDM), although this finding has not been confirmed by other studies. The discrepancy may be partially explained by the frequent coexistence in NIDDM patients of other pathologies, such as essential hypertension, and by the presence of(More)
The vasoconstrictor activity of sumatriptan and ergotamine were compared by injecting these drugs in the hand vein of migraine subjects. We used the "venotest method", which permits the evaluation of the venoconstrictor effect of small doses of drugs, acting locally in the hand vein. Sumatriptan injected at increasing doses in the hand vein provoked(More)
Histamine is able to induce spontaneous-like headache attacks in migraine and cluster headache subjects. Therefore, it has been considered as a possible agent in the pathogenesis of headache. Histamine desensitization is used for the treatment of cluster and other chronic headaches like migrains with interparoxysmal headache. However, it is unknown whether(More)
BACKGROUND In haemodialysis (HD) patients, anaemia is associated with reduced survival. Despite treatment with erythropoiesis-stimulating agents (ESAs), a large number of patients with chronic kidney disease show resistance to this therapy and require much higher than usual doses of ESAs in order to maintain the recommended haemoglobin (Hb) target, and(More)
To evaluate the role of endothelin-1 (ET-1), a vasoconstrictor and mitogenic peptide synthesized by endothelial cells, on the endothelial dysfunction in non-insulin-dependent diabetic (type 2) patients, we have measured the circulating ET-1 levels in 25 patients with and without clinically evident vascular complications and in a control group. Circulating(More)
25-HYDROXYVITAMIN D STATUS AND BONE MINERAL DENSITY OF KOREAN WOMEN. JH KIM~ SW K1M, SJ MOON, SK LIM. Dept. of Food and Nutrition, Dept. of Internal Medicine, Yonsei University. Seoul, Korea. Level of serum 25-hydroxyvitamin D(25-OHD) in 179 Korean women aged from 20 to 75 years old was investigated by HPLC (High Pressure Liquid Chromatography). Related(More)
Melatonin (MEL), the main hormone produced by the pineal gland, seems to exert antineoplastic activity both in vitro and in vivo. Moreover, several studies reported increased melatonin blood levels in cancer patients. Plasma melatonin concentrations were determined in 46 patients with multiple myeloma and in 31 age matched healthy subjects (57.8 +/- 6.9(More)
At present, the most commonly used method for assessing bone density is dual' energy X-ray absorptiometry (DEXA). However, this method has some disadvantages such as radiation exposure (though low) and expensiveness. A new ultrasound technique has bean recently proposed for evaluating skeletal integrity by measuring speed of sound and ultrasonic attenuation(More)
LOAD IN UNPROTECTED FALLS ON THE HIP V. Askegaard, J.B. Lauritzen. Department of Orthopaedi~ Surgery, Bispebjerg Hospital, University of Copenhagen, Department of Structural Engineering, Technical University of Der~ark. The fracture load in the proximal femur ranges from 2.0 to 6.3 kN (i) ,but no data are available about the impact force acting on the hip(More)