Adriana Martín

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OBJECTIVE The objective of this study is to evaluate the economic benefits of immunoglobulin replacement therapy achieved subcutaneously (subcutaneous immunoglobulin, SCIG) by the rapid push method compared to intravenous infusion therapy (intravenous immunoglobulin, IVIG) in primary immune deficiency (PID) patients from the healthcare system perspective in(More)
Every day more and more users with different abilities and/or temporally or permanent disabilities are accessing the Web, and many of them have difficulties in reaching the desired information. However, the development of this kind of software is complicated for several reasons. Though some of them are technological, the majority are related with the need(More)
Usually, a huge number of tools and proposals help developers assess Accessibility of Web applications; however, looking from the designer perspective, there is no such a similar situation. It seems that creating accessible Web sites is more expensive and complicated than creating Web sites and then assessing/modifying them. Although this feeling may be(More)
Although Accessibility has not yet gained much recognition as a crucial non-functional requirement like security, performance, accuracy and usability, it is a vital attribute for people with disabilities. Developing accessible Web applications is usually hard for several reasons. Firstly, there is a significant knowledge gap between developers and(More)
The lack of adequate Accessibility of Web sites remains a problem for blind users and other people with disabilities. The process of engineering accessible Web applications involves several issues, which include content, presentation and pragmatic issues that, fortunately, are currently addressed by some standard models such as the W3C's Accessibility(More)
The design and synthesis of enhanced membrane-intercalating biomaterials for drug delivery or vascular membrane targeting is currently challenged by the lack of screening and prediction tools. The present work demonstrates the generation of a Quantitative Structural Activity Relationship model (QSAR) to make a priori predictions. Amphiphilic macromolecules(More)
Currently, Web-based applications without personalization and developed with "ad hoc" practices are requiring substantial evolution. Particularly, e-commerce applications are implicitly bound to a fully customisable fashion, attending individual users or group of users needs. Hence, personalization is a leader performance feature of today's Web applications(More)
Objectives To assess the safety and efficacy of Hizentra™, a 20% human IgG for subcutaneous administration, in a cohort of patients with primary immunodeficiency disorders (PID) after a dose equivalent switch from their previous treatment. Methods A cohort study of 57 PID patients was reviewed 3 months post-transition to the 20% Subcutaneous Immunoglobu-lin(More)
BACKGROUND Hypertension is associated with increased cardiovascular deaths in patients with acromegaly. OBJECTIVE To evaluate the accuracy of blood pressure (BP) by 24-h ambulatory blood pressure monitoring (ABPM) and office BP measurements to represent the real BP status in acromegalic patients and its relationship with acromegalic activity and(More)